肺癌中多种血清蛋白的研究。免疫球蛋白A、G、M、触珠蛋白、α-1-抗胰蛋白酶、α-2-巨球蛋白
[Study of various serum proteins in lung cancer. Immunoglobulins A, G, M, haptoglobin, alpha-1-antitrypsin, alpha-2-macroglobulin].
作者信息
Bata J, Colobert L, Biron A, Brune J
出版信息
Ann Biol Clin (Paris). 1977;35(4):297-303.
A statistical study of the plasma concentration of immunoglobulin, alpha-1-antitrypsin, haptoglobin, and alpha-2-macroglobulin in 153 patients with primary carcinoma of the lung showed a strong increase in alpha-1-antitrypsin, haptoglobin and A and C immunoglobulins, whilst alpha-2-macroglobulin increases very moderately, and IgM does not vary. The relationships between variables are also modified, thus there appears a correlation between IgA and IgG to the detriment of the IgG/IgM relationship. Furthermore the coefficient of the correlation IgG/alpha-2-macroblobulin is lower in cancer patients.
一项针对153例原发性肺癌患者的免疫球蛋白、α-1抗胰蛋白酶、触珠蛋白和α-2巨球蛋白血浆浓度的统计研究表明，α-1抗胰蛋白酶、触珠蛋白以及A和C免疫球蛋白显著升高，而α-2巨球蛋白升高幅度很小，IgM则无变化。变量之间的关系也发生了改变，因此出现了IgA与IgG之间的相关性，损害了IgG/IgM的关系。此外，癌症患者中IgG/α-2巨球蛋白的相关系数较低。
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