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[心脏与婴儿猝死。100例解剖病理学研究]

[Heart and sudden infant death. Anatomopathological study of 100 cases].

作者信息

Pelletier-Leroy B, Nomballais M F, Verriele V, Mouzard A

机构信息

Laboratoire d'anatomie Pathologique A, Hôtel-Dieu, CHU, Nantes, France.

出版信息

Arch Pediatr. 1995 Oct;2(10):965-72. doi: 10.1016/0929-693x(96)89892-7.

Abstract

BACKGROUND

Post-mortem examination of infants with sudden infant death syndrome (SIDS) is essential for understanding the cause and/or mechanism of death. This study aims to evaluate the contributions of heart in SIDS.

POPULATION AND METHODS

Between 1981 and 1990, the CHU of Nantes carried out autopsies on 162 cases of sudden infant death syndrome. One hundred files were accepted for this retrospective study because a second recent macroscopic and microscopic (11 samples for each heart) examination of heart was possible.

RESULTS

The weight of hearts was not increased, except in one case. Macroscopic examination did not reveal any cardiac abnormalities. Histological examination confirmed the lesions initially observed in 11 cases and probably responsible for their death.

CONCLUSIONS

This study underlines the importance of studying numerous samples of each heart of microscopic examination of many sections.

摘要

背景

对婴儿猝死综合征(SIDS)患儿进行尸检对于了解死亡原因和/或机制至关重要。本研究旨在评估心脏在婴儿猝死综合征中的作用。

研究对象与方法

1981年至1990年间,南特大学中心医院对162例婴儿猝死综合征病例进行了尸检。本回顾性研究采用了其中100份档案,因为可以对心脏进行近期的第二次大体和显微镜检查(每个心脏取11个样本)。

结果

除1例病例外,心脏重量未增加。大体检查未发现任何心脏异常。组织学检查证实了最初在11例病例中观察到的病变,这些病变可能是导致其死亡的原因。

结论

本研究强调了对每个心脏的多个样本进行多切片显微镜检查的重要性。

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