对照组和大便失禁患者肛管的测压不对称性。

Manometric asymmetry in the anal canal in controls and patients with fecal incontinence.

作者信息

Williams N, Barlow J, Hobson A, Scott N, Irving M

机构信息

Department of Surgery, University of Manchester, Hope Hospital, Salford, United Kingdom.

出版信息

Dis Colon Rectum. 1995 Dec;38(12):1275-80. doi: 10.1007/BF02049152.

DOI:10.1007/BF02049152

PMID:7497839

Abstract

PURPOSE

This study was designed to ascertain the existence of manometric asymmetry in the anal canal in controls and in patients with fecal incontinence.

METHODS

A computerized manometric technique with an eight-channel perfusion catheter was used. Coefficient of variation (CV, a mathematical expression of the degree or magnitude of deviation of a set of data points from the mean) was developed in this study as an index of anal canal manometric asymmetry.

RESULTS

At 1 cm from the anal verge, mean CV was 9.3 and 8.7 percent in asymptomatic control males and females, respectively. During a maximum voluntary squeeze effort, mean CV in control males was 9.3 percent and was not significantly different (P = 0.28) from that in control females (7.8 percent). In 14 consecutive female patients with fecal incontinence, mean CV at rest (1 cm from the anal verge) was 21 percent and was significantly higher (P < 0.01) than in control females. Similarly, during a maximum voluntary squeeze effort, mean CV in patients with fecal incontinence was 20.5 percent and was significantly higher (P < 0.01) than in the female control group (7.8 percent).

CONCLUSION

It is concluded that CV, a method of expressing anal sphincter manometric asymmetry, is a useful manometric parameter in the assessment of anorectal function.

摘要

目的

本研究旨在确定对照组及大便失禁患者肛管测压不对称的情况。

方法

采用带有八通道灌注导管的计算机化测压技术。本研究开发了变异系数（CV，一组数据点相对于均值的偏离程度或大小的数学表达式）作为肛管测压不对称的指标。

结果

在距肛缘1厘米处，无症状对照男性和女性的平均CV分别为9.3%和8.7%。在最大自主收缩时，对照男性的平均CV为9.3%，与对照女性（7.8%）相比无显著差异（P = 0.28）。在连续14例大便失禁的女性患者中，静息时（距肛缘1厘米处）的平均CV为21%，显著高于对照女性（P < 0.01）。同样，在最大自主收缩时，大便失禁患者的平均CV为20.5%，显著高于女性对照组（7.8%）（P < 0.01）。