Chyrek-Borowska S, Obrzut D, Hofman J
Arch Immunol Ther Exp (Warsz). 1978;26(1-6):709-12.
Investigation of magnesium, blood histamine level and eosinophilia were carried out on 28 bronchial asthma patients during the exacerbation of asthma and in asymptomatic period of the disease. Control group consisted of 30 healthy persons. It was found that during asthma attack in the patients with atopic asthma magnesium level in blood and erythrocytes decreased which is correlated to the rise in histamine level and the number of eosinophils in blood. This relationship was less marked in patients with non-atopic asthma. Results obtained are a further confirmation of the role of magnesium ions in the pathomechanism of immediate allergic reactions in humans and its participation in the immunological release of histamine.
对28例支气管哮喘患者在哮喘发作期和疾病无症状期进行了镁、血组胺水平及嗜酸性粒细胞增多情况的调查。对照组由30名健康人组成。发现特应性哮喘患者在哮喘发作时，血液和红细胞中的镁水平降低，这与组胺水平升高及血液中嗜酸性粒细胞数量增加相关。这种关系在非特应性哮喘患者中不太明显。所得结果进一步证实了镁离子在人类速发型过敏反应发病机制中的作用及其参与组胺的免疫释放。
