Gottlob I, Wizov S S, Reinecke R D
Foerdeber Eye Movement Center for Children, Wills Eye Hospital, Department of Ophthalmology, Jefferson Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
Invest Ophthalmol Vis Sci. 1995 Dec;36(13):2768-71.
Nystagmus, head nodding, and anomalous head position are symptoms of spasmus nutans. This disorder appears in early childhood and is thought to be self-limited. However, the visual outcome of patients with spasmus nutans is unclear. The resolution of nystagmus has not been proven with quantitative eye movement recordings. The purpose of this study was to perform long-term follow-up examinations (mean, 5.5 years) of patients with spasmus nutans.
Ten patients with spasmus nutans were followed up clinically until a mean age of 7 years. Included were quantitative eye and head movement recordings.
At their last examination (mean age, 7.1 years), visual acuity in four patients was 20/20 in both eyes, in five patients it was 20/30 or better in at least one eye, and in one patient it was 20/50 in each eye. Three patients had orthotropia with normal stereo acuity. The remaining patients had esotropia, dissociated vertical deviation, amblyopia, or latent nystagmus. All patients had fine, intermittent asymmetric, pendular nystagmus on eye movement recordings.
Good visual acuity can be expected in patients with spasmus nutans; one third have normal stereo acuity. However, subclinical nystagmus persists until at least 5 to 12 years of age.
眼球震颤、点头和异常头位是痉挛性斜颈的症状。这种疾病出现在儿童早期，被认为是自限性的。然而，痉挛性斜颈患者的视力预后尚不清楚。眼球震颤的缓解尚未通过定量眼动记录得到证实。本研究的目的是对痉挛性斜颈患者进行长期随访检查（平均5.5年）。
对10例痉挛性斜颈患者进行临床随访，直至平均年龄7岁。包括定量眼动和头部运动记录。
在最后一次检查时（平均年龄7.1岁），4例患者双眼视力为20/20，5例患者至少一只眼视力为20/30或更好，1例患者双眼视力为20/50。3例患者有正位视且立体视正常。其余患者有内斜视、分离性垂直偏斜、弱视或潜在性眼球震颤。所有患者在眼动记录中均有细微、间歇性不对称、摆动性眼球震颤。
痉挛性斜颈患者有望获得良好视力；三分之一患者立体视正常。然而，亚临床眼球震颤至少持续到5至12岁。
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