细胞因子与骨髓移植
Cytokines and bone marrow transplantation.
作者信息
Takaku F
机构信息
International Medical Center of Japan, Tokyo, Japan.
出版信息
J Cancer Res Clin Oncol. 1995;121(12):701-9. doi: 10.1007/BF01213315.
Abstract
This article summarizes the various current uses of cytokines, and bone marrow and peripheral blood stem cell transplantation for cancer treatment. Interferons, interleukin-2 and hematopoietic growth factors are extensively used for the treatment of hematopoietic as well as nonhematopoietic malignancies, either as the main therapeutic agents or as an adjuvant. Research on gene therapy using cytokines is in progress. Stem cell transplantation is also discussed in the context of gene therapy of cancer. Gene therapy is expected to become a future modality in cancer treatment.
摘要
本文总结了细胞因子、骨髓和外周血干细胞移植目前在癌症治疗中的各种应用。干扰素、白细胞介素-2和造血生长因子广泛用于治疗造血系统以及非造血系统恶性肿瘤，既作为主要治疗药物，也作为辅助药物。使用细胞因子的基因治疗研究正在进行中。干细胞移植也在癌症基因治疗的背景下进行了讨论。基因治疗有望成为未来癌症治疗的一种方式。
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