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一种辐射后细胞存活的随机模型。

A stochastic model for cell survival after irradiation.

作者信息

Bansal B N, Gupta P C

出版信息

Biometrics. 1978 Dec;34(4):653-61.

PMID:749947
Abstract

A theory of cell survival after irradiation has been developed based on a single compartment model of a living cell and taking into account a recovery phenomenon. The basis of the model is the assumption that once a cell is repaired, it will behave like a normal cell if irradiated further. Theoretical expressions for the probability of survival or damage of an irradiated cell at an arbitrary instant in time have been obtained for a constant damage rate and a general repair-time distribution. An application of these derived expressions has been made to experimental data.

摘要

基于活细胞的单室模型并考虑恢复现象,已建立了一种辐照后细胞存活理论。该模型的基础是假设一旦细胞得到修复,如果再次受到辐照,它将表现得像正常细胞一样。对于恒定的损伤率和一般的修复时间分布,已获得了辐照细胞在任意时刻存活或受损概率的理论表达式。这些推导表达式已应用于实验数据。

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