Swanson W H, Fish G E
Retina Foundation of the Southwest, Dallas, Texas 75231, USA.
J Opt Soc Am A Opt Image Sci Vis. 1995 Oct;12(10):2230-6. doi: 10.1364/josaa.12.002230.
Reduced foveal cone optical density in diseased eyes with normal acuity can affect color matches. Using field diameters of 1 degree, 2 degrees, 4 degrees, and 8 degrees, we measured mean color-match midpoints and match widths in patients who had good acuity and who exhibited three categories of eye disease: hereditary macular degeneration (n = 12), retinitis pigmentosa (n = 19), and glaucoma (n = 18). Results were compared with those for normal observers of comparable ages. Mean color-match midpoints were abnormal only for the population with hereditary macular degeneration, indicating a reduction in cone optical density in the central 4 degrees. Mean color-match widths were enlarged for both hereditary macular degeneration and retinitis pigmentosa, a result consistent with a reduction in the number of foveal cones.
视力正常的患病眼睛中中央凹视锥细胞光学密度降低会影响颜色匹配。我们使用1度、2度、4度和8度的视野直径，测量了视力良好且患有三类眼病的患者的平均颜色匹配中点和匹配宽度，这三类眼病分别为：遗传性黄斑变性（n = 12）、视网膜色素变性（n = 19）和青光眼（n = 18）。将结果与年龄相仿的正常观察者的结果进行比较。仅遗传性黄斑变性人群的平均颜色匹配中点异常，表明中央4度范围内视锥细胞光学密度降低。遗传性黄斑变性和视网膜色素变性的平均颜色匹配宽度均增大，这一结果与中央凹视锥细胞数量减少一致。
