Inhibition of cell-free protein synthesis by analogues of aurintricarboxylic acid.
作者信息
Kreamer B L, Anderson J, Liu D S, Sparks M B, Richardson A
出版信息
Can J Biochem. 1978 Dec;56(12):1162-7. doi: 10.1139/o78-182.
DOI:10.1139/o78-182
PMID:750075
Abstract
Aurintricarboxylic acid is a potent inhibitor of cell-free protein synthesis by the post-mitochondrial supernatant of chick brain and the translation of mRNA by wheat germ lysate. Comparison of commercially available and chemically synthesized analogues of aurintricarboxylic acid indicates that the unique aurin triphenyl methane ring system and the carboxylic acid groups are both necessary for inhibition of cell-free protein synthesis in both systems.
摘要
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