[金精三羧酸作用下细胞周期中蛋白质合成抑制的新研究：大蒜分生组织细胞的研究]
[New researches on protein synthesis inhibition under the action of aurintricarboxylic acid during cell cycle : Study on meristematic cells of Allium sativum L].
作者信息
Lévy F, Bournique C P, Deysson G
出版信息
C R Acad Hebd Seances Acad Sci D. 1976 Jun 14;282(22):1951-4.
PMID:821665
Abstract
Aurin tricarboxylic acid, an inhibitor of protein synthesis, prevents cells from entering mitosis in Allium sativum L. root meristems. When the uptake of 3H-leucine comes back up to the control rate after removal of roots from the drug, mitotoic activity is resumed. Furthermore, the percent of labelled cells obtained by continuous labelling with H3-thymidine shows a reversible arrest of cell progress from G1 to S.
摘要
金精三羧酸是一种蛋白质合成抑制剂，可阻止大蒜根尖分生组织中的细胞进入有丝分裂。当从药物中取出根后，3H-亮氨酸的摄取恢复到对照速率时，有丝分裂活性就会恢复。此外，通过用H3-胸腺嘧啶连续标记获得的标记细胞百分比显示细胞从G1期到S期的进程出现可逆性停滞。
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C R Acad Hebd Seances Acad Sci D. 1976 Jun 14;282(22):1951-4.
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