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[神经科诊所是否需要内设脑脊液/神经化学实验室?对289家神经科诊所的调查结果]

[Does a neurologic clinic need an inhouse cerebrospinal fluid/neurochemical laboratory? Results of a survey of 289 neurological clinics].

作者信息

Scharein S, Kunze K

机构信息

Neurologische Klinik und Poliklinik, Universitätkrankenhaus Hamburg Eppendorf.

出版信息

Nervenarzt. 1995 Oct;66(10):770-6.

PMID:7501093
Abstract

In 1993 and 1994 an official inquiry was carried out by the Deutsche Gesellschaft für Neurologie into the existence of neurochemical laboratories in departments of neurology throughout Germany. The following results were obtained. Neurochemical laboratories are more often seen in neurology departments involved in routine or emergency diagnosis than in departments engaged only in rehabilitation. Nearly all departments with an intensive care unit in a university hospital (91%) and nearly half of those outside the university (46%) have their own neurochemical laboratory. Departments with their own neurochemical laboratories are characterized by the use of specialized immunological diagnosis, especially of the cerebrospinal fluid (e.g., immunoglobulins, isoelectric focusing), in contrast to departments that are not working in the field of emergency medicine and are not equipped with their own neurochemical laboratories. The latter mostly carry out screening tests (e.g., antiepileptic drug monitoring, tumor markers). The existence of a neurochemical laboratory in a neurology department does not lead to an undifferentiated increase in the number of laboratory tests, but reflects the need for specialized diagnosis in CSF and neuroimmunology.

摘要

1993年和1994年,德国神经病学协会对德国各地神经病学部门中神经化学实验室的情况进行了官方调查。结果如下。与仅从事康复治疗的部门相比,神经化学实验室在参与常规或急诊诊断的神经病学部门中更为常见。大学医院中几乎所有设有重症监护病房的部门(91%)以及大学外近一半的部门(46%)都有自己的神经化学实验室。拥有自己神经化学实验室的部门的特点是使用专门的免疫诊断方法,尤其是针对脑脊液的诊断(例如免疫球蛋白、等电聚焦),这与那些不从事急诊医学领域工作且没有配备自己神经化学实验室的部门形成对比。后者大多进行筛查测试(例如抗癫痫药物监测、肿瘤标志物检测)。神经病学部门中存在神经化学实验室并不会导致实验室检查数量无差别地增加,而是反映了脑脊液和神经免疫学方面进行专门诊断的需求。

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