Jost W H, Kirchhöfer U, Houy S, Schimrigk K
Neurologische Klinik, Universität des Saarlandes, Homburg/Saar.
Nervenarzt. 1995 Oct;66(10):777-80.
Several tests of cardiovascular and gastrointestinal function have been approved for the diagnosis of autonomic regulation dysfunction in Parkinson's disease. In the present study we compared the diagnostic value of the sympathetic skin response (SSR) with the established methods. Ninety percent of the 20 patients we examined (10 women, 10 men, 46 to 80 years) showed pathological results in the cardiovascular function test. Fifty-five percent had a prolonged colon transit, indicating a gastrointestinal dysfunction. We saw pathologically prolonged latencies of the SSR in 35% of the patients, 55% had borderline results. Three of the 20 patients had pathological results in all of the functions examined. Half of the patients had two pathological results, whereas 7 patients were pathological in only one of the three examinations. We were unable to establish any correlation between the SSR and other results, and we also found no relationship between prolonged SSR and the duration of the disease.
多项心血管和胃肠功能测试已被批准用于诊断帕金森病中的自主神经调节功能障碍。在本研究中，我们将交感皮肤反应（SSR）的诊断价值与既定方法进行了比较。我们检查的20名患者（10名女性，10名男性，46至80岁）中有90%在心血管功能测试中显示出病理结果。55%的患者结肠运输时间延长，表明存在胃肠功能障碍。我们发现35%的患者SSR潜伏期病理性延长，55%的患者结果处于临界状态。20名患者中有3名在所有检查的功能中都有病理结果。一半的患者有两项病理结果，而7名患者在三项检查中只有一项存在病理情况。我们无法确定SSR与其他结果之间的任何相关性，并且我们也未发现SSR延长与疾病持续时间之间存在关联。
