Catalano C, Pavone P, Laghi A, Clementi M, Scipioni A, Sarrantonio A, Faroni J, Passariello R
Istituto di Radiologia, Università La Sapienza, Roma.
Radiol Med. 1995 Sep;90(3):262-8.
Magnetic resonance imaging of the pancreas has been, limited by a series of artifacts with a resulting poor contrast to noise ratio. Nevertheless, technological progress has allowed to reduce not only scanning time but also the number of artifacts, by increasing the number of excitations and matrix size. Moreover, tissue contrast can now be modified. In our study performed on 5 normal volunteers and 20 patients with different pancreatic diseases conditions, fast SE sequences with and without fat suppression were used, with an overall increase in contrast to noise ratio. In all patients MR images allowed the accurate definition of the lesions: in 8 adenocarcinoma patients the lesion could be depicted, including the 2 lesions CT had poorly demonstrated. Also in the 3 patients with endocrine tumors, MRI depicted small tumors which were later confirmed at surgery. This new protocol makes MRI a very sensitive and accurate tool in the study of neoplastic and inflammatory pancreatic diseases thus, MRI is not only a complementary tool to CT but an even better study technique. In particular, its higher contrast to noise ratio allows a dramatic improvement in the depiction of small solid lesions, especially those not altering pancreatic outline. This study proves that MRI, when adequately performed, is a very accurate tool to study, in a very short time, the pancreas and peripancreatic region, yielding much better results than all the other diagnostic imaging modalities.
胰腺的磁共振成像一直受到一系列伪影的限制,导致对比度噪声比很差。然而,技术进步不仅缩短了扫描时间,还通过增加激励次数和矩阵大小减少了伪影数量。此外,现在可以改变组织对比度。在我们对5名正常志愿者和20名患有不同胰腺疾病的患者进行的研究中,使用了有和没有脂肪抑制的快速SE序列,总体上提高了对比度噪声比。在所有患者中,MR图像都能准确界定病变:在8例腺癌患者中,可以描绘出病变,包括2例CT显示不佳的病变。在3例内分泌肿瘤患者中,MRI也显示出小肿瘤,后来手术证实了这些肿瘤。这种新方案使MRI成为研究胰腺肿瘤性和炎性疾病的非常敏感和准确的工具。因此,MRI不仅是CT的补充工具,而且是一种更好的研究技术。特别是,其较高的对比度噪声比能显著改善对小实性病变的描绘,尤其是那些不改变胰腺轮廓的病变。这项研究证明,当操作适当时,MRI是在短时间内研究胰腺和胰腺周围区域的非常准确的工具,其结果比所有其他诊断成像方式都要好得多。