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[八旬老人的心脏手术]

[Cardiac surgery in octogenarians].

作者信息

Stevens R, Gersbach P, Ruchat P, Hurni M, Stumpe F, Fischer A, Sadeghi H

机构信息

Service de chirurgie cardiovasculaire, CHUV, Lausanne.

出版信息

Schweiz Med Wochenschr. 1995 Oct 28;125(43):2084-9.

PMID:7502008
Abstract

37 patients aged 80 or over underwent cardiac surgery during an 11-year period. Operative indications included angina, dyspnea and syncope. The majority of patients (n = 32) had a left ventricular ejection fraction greater than 0.5. There were 28 aortic valve procedures, of which seven were combined with coronary artery bypass grafts (CABG), and 2 with mitral valve repair; in addition, 7 isolated CABG procedures and one isolated mitral valve repair were performed. 36-day mortality was 5.4% (2 patients); 9 patients died at a later date (2.5 to 118 months after surgery). The most frequent postoperative complications were atrial fibrillation, pulmonary infection or atelectasis, transient delirium and atrioventricular conduction disturbances. Mean hospital stay was 14.5 days. 1- and 5-year actuarial survival rates were 83% and 57%. In a control group of patients aged 60-69 matched for preoperative characteristics, there were no in-hospital fatalities and 1- and 5-year survival were, respectively, 100% and 82%. Among complications, only conduction disturbances and transient delirium were significantly more frequent in the octogenarian group. At follow-up, the proportion of severely symptomatic octogenarians had diminished to 24% from 84%. In conclusion, cardiac surgery can be performed on octagenarians with adequate myocardial reserve, exposing them to a perioperative mortality that is in the range of younger age groups while offering an equivalent prospect for functional improvement.

摘要

在11年期间,37名80岁及以上的患者接受了心脏手术。手术指征包括心绞痛、呼吸困难和晕厥。大多数患者(n = 32)的左心室射血分数大于0.5。共进行了28例主动脉瓣手术,其中7例合并冠状动脉旁路移植术(CABG),2例进行二尖瓣修复;此外,还进行了7例单纯CABG手术和1例单纯二尖瓣修复手术。36天死亡率为5.4%(2例患者);9例患者在术后较晚时间死亡(术后2.5至118个月)。最常见的术后并发症是房颤、肺部感染或肺不张、短暂谵妄和房室传导障碍。平均住院时间为14.5天。1年和5年的精算生存率分别为83%和57%。在一组术前特征匹配的60 - 69岁对照组患者中,无院内死亡,1年和5年生存率分别为100%和82%。在并发症方面,只有传导障碍和短暂谵妄在八旬老人组中明显更常见。随访时,有严重症状的八旬老人比例从84%降至24%。总之,对于心肌储备充足的八旬老人可以进行心脏手术,使其围手术期死亡率处于较年轻年龄组的范围内,同时功能改善前景相当。

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