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[血液中血浆蛋白在维持其水解特性相对恒定方面的重要性]

[The importance of the plasma proteins of the blood in maintaining the relative constancy of its hydrolytic properties].

作者信息

Korot'ko G F, Vepritskaia E A, Iuabova E Iu

出版信息

Fiziol Zh Im I M Sechenova. 1993 Sep;79(9):72-80.

PMID:7505697
Abstract

Effects of hypervolemia, dehydration, activation and inhibition of urine-formation, i. v. administration of amylase and pepsinogen, experimental acute pancreatitis upon amylolytic activity of blood plasma, contents of pepsinogen in it, amylase and pepsinogen within the blood plasma protein factions, and excretion of enzymes with the urine, were studied in dogs. The data obtained suggest an important role of interconnection between amylase and pepsinogen with the plasma proteins in their renal and extrarenal excretion from the organism and in maintenance of a relative constancy of the contents and activity of enzymes in the blood. The affinity of the plasma proteins to their stains can indirectly characterise the transport capacity of the proteins in respect to amylase and pepsinogen.

摘要

在犬身上研究了高血容量、脱水、尿液生成的激活与抑制、静脉注射淀粉酶和胃蛋白酶原、实验性急性胰腺炎对血浆淀粉酶活性、血浆中胃蛋白酶原含量、血浆蛋白组分中的淀粉酶和胃蛋白酶原以及酶随尿液排泄的影响。所获得的数据表明,淀粉酶和胃蛋白酶原与血浆蛋白之间的相互联系在它们从机体的肾内和肾外排泄以及维持血液中酶的含量和活性的相对恒定方面起着重要作用。血浆蛋白对其染色剂的亲和力可间接表征蛋白质对淀粉酶和胃蛋白酶原的转运能力。

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