Riley M
Marine Biological Laboratory, Woods Hole, Massachusetts 02543.
Microbiol Rev. 1993 Dec;57(4):862-952. doi: 10.1128/mr.57.4.862-952.1993.
A list of currently identified gene products of Escherichia coli is given, together with a bibliography that provides pointers to the literature on each gene product. A scheme to categorize cellular functions is used to classify the gene products of E. coli so far identified. A count shows that the numbers of genes concerned with small-molecule metabolism are on the same order as the numbers concerned with macromolecule biosynthesis and degradation. One large category is the category of tRNAs and their synthetases. Another is the category of transport elements. The categories of cell structure and cellular processes other than metabolism are smaller. Other subjects discussed are the occurrence in the E. coli genome of redundant pairs and groups of genes of identical or closely similar function, as well as variation in the degree of density of genetic information in different parts of the genome.
给出了一份目前已鉴定出的大肠杆菌基因产物列表，以及一份参考文献目录，该目录为有关每个基因产物的文献提供了指引。一种对细胞功能进行分类的方案被用于对迄今已鉴定出的大肠杆菌基因产物进行分类。一项统计表明，与小分子代谢相关的基因数量与与大分子生物合成及降解相关的基因数量处于同一量级。一个大的类别是tRNA及其合成酶的类别。另一个是转运元件的类别。细胞结构及除代谢之外的细胞过程的类别则较小。讨论的其他主题包括大肠杆菌基因组中功能相同或极为相似的冗余基因对和基因簇的存在情况，以及基因组不同区域遗传信息密度程度的差异。
