Karp P D, Riley M, Paley S M, Pellegrini-Toole A, Krummenacker M
Pangea Systems Inc., 4040 Campbell Avenue, Menlo Park, CA 94025, USA and Marine Biological Laboratory, Woods Hole, MA 02543, USA.
Nucleic Acids Res. 1999 Jan 1;27(1):55-8. doi: 10.1093/nar/27.1.55.
The EcoCyc database describes the genome and gene products of Escherichia coli, its metabolic and signal-transduction pathways, and its tRNAs. The database describes 4391 genes of E.coli, 695 enzymes encoded by a subset of these genes, 904 metabolic reactions that occur in E.coli, and the organization of these reactions into 129 metabolic pathways. The EcoCyc graphical user interface allows scientists to query and explore the EcoCyc database using visualization tools such as genomic-map browsers and automatic layouts of metabolic pathways. EcoCyc has many references to the primary literature, and is a (qualitative) computational model of E. coli metabolism. EcoCyc is available at URL http://ecocyc. PangeaSystems.com/ecocyc/
EcoCyc数据库描述了大肠杆菌的基因组和基因产物、其代谢和信号转导途径以及tRNA。该数据库描述了大肠杆菌的4391个基因、这些基因子集中编码的695种酶、大肠杆菌中发生的904种代谢反应，以及这些反应在129条代谢途径中的组织方式。EcoCyc图形用户界面允许科学家使用基因组图谱浏览器和代谢途径自动布局等可视化工具查询和探索EcoCyc数据库。EcoCyc有许多来自原始文献的参考文献，并且是大肠杆菌代谢的（定性）计算模型。可通过网址http://ecocyc.PangeaSystems.com/ecocyc/获取EcoCyc。
