Negative effects of chronic hemicerebellectomy of epileptiform after-discharges elicited by focal cortical stimulation in baboons (Papio papio).

The influence of chronic hemicerebellectomy on cortical epileptiform after-discharge (AD) induced by focal electrical stimulation was studied in the baboon. These preliminary results include 22 ADs elicited from motor cortex and 22 ADs elicited from premotor cortex before and after hemicerebellectomy. Only full-developed, generalized seizures with postictal silence were considered. EEG morphology, average duration and average current threshold were compared for each set of ictal events. No significant differences were found before and after hemicerebellectomy.