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[I期睾丸肿瘤的内分泌学与生育能力]

[Endocrinology and fertility in stage I testicular tumor].

作者信息

Joos H, Chandra I, Frick J

机构信息

Urologische Abteilung, Landeskrankenanstalten Salzburg, Osterreich.

出版信息

Helv Chir Acta. 1993 Dec;60(3):367-70.

PMID:7509783
Abstract

The situation of endocrinology and fertility of patients suffering from testicular cancer stage I (Peckham) with good survival rates were evaluated before semicastration. The value of beta-hCG is of great importance. According to this criteria 3 groups were formed. beta-hCG positive tumors, beta-hCG positive tumors out of the blood sample of the vena spermatica after ablation of the testis tumor and beta-hCG negative tumors. The histology is of secondary importance. 54 patients with testicular cancer were evaluated in this study. From 37 patients it was possible to get a spermiogram before semicastration. For the analysis of the spermiogram the values of LH, FSH, Testosterone and E2 are responsible. The values of beta-hCG in the serum from the periphery is of great importance, while a single elevation of beta-hCG in the serum out of the v.spermatica does not change the endocrinology. The question of kryosperm conservation is according to these parameters better evaluable.

摘要

对I期睾丸癌(佩卡姆分期)且生存率良好的患者在内分泌和生育能力方面的情况进行了半阉割前评估。β-人绒毛膜促性腺激素(β-hCG)的值非常重要。根据该标准形成了3组,即β-hCG阳性肿瘤组、睾丸肿瘤切除后精索静脉血样中β-hCG阳性肿瘤组和β-hCG阴性肿瘤组。组织学为次要因素。本研究评估了54例睾丸癌患者。其中37例患者在半阉割前能够获得精子图。对于精子图的分析,促黄体生成素(LH)、促卵泡生成素(FSH)、睾酮和雌二醇(E2)的值起作用。外周血清中β-hCG的值非常重要,而精索静脉血中β-hCG单次升高不会改变内分泌情况。根据这些参数,冷冻精子保存的问题更易于评估。

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