Raimondi E, Moralli D, De Carli L, Ceratto N, Balzaretti M, Leube R, Collin C, Romano V
Dipartimento di Genetica e Microbiologia A. Buzzati Traverso, Università di Pavia, Italy.
Cytogenet Cell Genet. 1994;66(3):162-3. doi: 10.1159/000133690.
We used fluorescence in situ hybridization to localize the human gene for cytokeratin 3 (KRT3), a member of the type II subfamily of cytokeratins, within the human genome. The results show that KRT3 is located within chromosome region 12q12-->q13. All human type II keratin genes mapped to date have been assigned to chromosome 12, where they are likely to be organized into one homotypic cluster.
我们运用荧光原位杂交技术，将细胞角蛋白3（KRT3）基因（细胞角蛋白II型亚家族的一员）定位到人类基因组中。结果显示，KRT3基因位于12号染色体区域12q12至q13。迄今所有已定位的人类II型角蛋白基因均被定位于12号染色体，它们可能在此形成一个同型基因簇。
