继发于分泌促甲状腺激素、促卵泡激素、α亚基和生长激素的垂体腺瘤的甲状腺功能亢进症。
Hyperthyroidism secondary to a pituitary adenoma secreting TSH, FSH, alpha-subunit and GH.
作者信息
Patrick A W, Atkin S L, MacKenzie J, Foy P M, White M C, MacFarlane I A
机构信息
Department of Endocrinology, Walton Hospital, Liverpool, UK.
出版信息
Clin Endocrinol (Oxf). 1994 Feb;40(2):275-8. doi: 10.1111/j.1365-2265.1994.tb02480.x.
A 51-year-old man had been treated for hyperthyroidism with antithyroid drugs for 8 years. He was then found to have a large pituitary adenoma with biochemical evidence of overproduction of TSH, FSH and alpha-subunit. Subsequent immunocytochemical and tissue culture studies confirmed secretion of these hormones. In addition, the tumour stained for GH and was capable of GH production in vitro. This combination of hormones produced by a pituitary adenoma has not been previously reported.
一名51岁男性曾用抗甲状腺药物治疗甲状腺功能亢进症8年。随后发现他患有巨大垂体腺瘤，并有促甲状腺激素（TSH）、促卵泡生成素（FSH）和α亚基分泌过多的生化证据。随后的免疫细胞化学和组织培养研究证实了这些激素的分泌。此外，肿瘤对生长激素（GH）染色阳性，且在体外能够产生GH。垂体腺瘤产生的这种激素组合此前未见报道。
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