骨髓中性粒细胞成熟过程中表面抗原的发育
Development of surface antigen during maturation of bone marrow neutrophil granulocytes.
作者信息
Evans W H, Mage M
出版信息
Exp Hematol. 1978 Jan;6(1):37-42.
The presence of neutrophil surface antigens on maturing bone marrow granulocytes was examined by indirect immunofluorescence and cellular immunoadsorption using heterologous antibody to mature neutrophil granulocytes. The results show that bone marrow neutrophils possess surface antigens that appear during cell maturation from myeloblasts. Fluorescent antibody capping and patching, indicators of antigen mobility, were more pronounced in mature than in immature cells. Neutrophil surface antigen development could also be demonstrated during granulocyte maturation in vitro.
利用针对成熟中性粒细胞的异源抗体，通过间接免疫荧光和细胞免疫吸附法检测了成熟骨髓粒细胞上中性粒细胞表面抗原的存在情况。结果表明，骨髓中性粒细胞具有在成髓细胞向细胞成熟过程中出现的表面抗原。作为抗原流动性指标的荧光抗体帽化和斑块化现象在成熟细胞中比在未成熟细胞中更明显。中性粒细胞表面抗原的发育也可在体外粒细胞成熟过程中得到证实。
Zotero 插件