Oberholzer M, Hubler M, Hell M, Spieler P, Oestreicher M
Institut für Pathologie der Universität Basel.
Verh Dtsch Ges Pathol. 1993;77:213-5.
An important prerequisite for densitometric and morphometric measurements on cytological specimens is the standardized cell preparation. Optimal results can only be achieved when the analyses are carried out on a regular monolayer of cell nuclei. Comparing the conventional cytological smear with a new centrifugation technique we demonstrate statistically significant differences of the two methods in texture, size and parameters describing the DNA content of normal and dysplastic urothelial cells.
对细胞学标本进行密度测定和形态测量的一个重要前提是标准化的细胞制备。只有在对规则的单层细胞核进行分析时才能获得最佳结果。通过将传统的细胞学涂片与一种新的离心技术进行比较,我们证明了这两种方法在描述正常和发育异常尿路上皮细胞的纹理、大小和DNA含量参数方面存在统计学上的显著差异。