Bittinger A, Barth P, von Keitz A, Thomas C
Zentrum für Pathologie und urologische Klinik der Philipps Universität Marburg.
Verh Dtsch Ges Pathol. 1993;77:209-12.
To assess the value of nuclear morphometry in the cytological diagnosis of urinary bladder carcinoma, washouts of the urinary bladder from 168 patients with histological established bladder cancer were studied. Morphometrical measurements were done on the nuclei of the exfoliated cells. This retrospective study showed that the nuclear parameter obtained by automated image analysis may be helpful in the differential diagnosis between neoplastic and non-neoplastic urinary bladder disease and correlate fairly with the classic histologic grading of malignancy in transitional cell carcinoma of the urinary bladder.
为评估细胞核形态计量学在膀胱癌细胞学诊断中的价值,对168例经组织学确诊为膀胱癌患者的膀胱冲洗液进行了研究。对脱落细胞的细胞核进行了形态计量学测量。这项回顾性研究表明,通过自动图像分析获得的核参数可能有助于鉴别肿瘤性和非肿瘤性膀胱疾病,并且与膀胱移行细胞癌的经典组织学恶性分级有较好的相关性。