某些二羟基香豆素及其同系物的降压活性。
Hypotensive activity of some dihydroxycoumarins and their congeners.
作者信息
Thakur R S, Bagadia S C, Sharma M L
出版信息
Experientia. 1978 Feb 15;34(2):158-9. doi: 10.1007/BF01944649.
PMID:75113
Abstract
Evaluation of the hypotensive activity of dihydroxy coumarins and their congeners reveal that the naturally occurring dimethoxy coumarin Scoparone has maximal activity, more significant than L-alpha-methyl dopa. Structure activity relationship studies are reported with an attempt to offer a probable mechanism of action.
摘要
对二羟基香豆素及其同系物的降压活性评估表明，天然存在的二甲氧基香豆素滨蒿内酯具有最大活性，比L-α-甲基多巴更显著。本文报道了结构活性关系研究，试图提供一种可能的作用机制。
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