[近期谷丙转氨酶（ALT）水平升高的血浆捐献者中乙肝病毒（HBV）和丙肝病毒（HCV）感染的患病率]

[Prevalence of HBV and HCV infections in plasma donors with recently increased ALT level].

作者信息

Li F

机构信息

Clinical Immunology Research Unit, Tongji Hospital, Tongji Medical University, Wuhan.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 1993 Aug;14(4):217-9.

PMID:7511485

Abstract

HCV and HBV markers in sera were examined in a group of donors (71 cases) who had a history of elevated ALT, and were compared with another group of blood donors (217 cases) who had no such a history. The results showed that the positive rates in both two groups of donors were 14.08% and 6.45% for anti-HCV, 3/8 and 2/13 for anti-HCV-IgM in anti-HCV positive cases, 2.82% and 0.46% for HBsAg, 32.39% and 25.35% for anti-HBs, 45.07% and 33.18% for anti-HBc, respectively (P < 0.05-0.01). It showed a good correlation between the positive rates of HCV and HBV markers and the times of ALT elevation.

摘要

对一组有谷丙转氨酶（ALT）升高病史的献血者（71例）检测血清中的丙肝病毒（HCV）和乙肝病毒（HBV）标志物，并与另一组无此病史的献血者（217例）进行比较。结果显示，两组献血者中抗-HCV阳性率分别为14.08%和6.45%，抗-HCV阳性病例中抗-HCV-IgM分别为3/8和2/13，HBsAg分别为2.82%和0.46%，抗-HBs分别为32.39%和25.35%，抗-HBc分别为45.07%和33.18%（P<0.05 - 0.01）。HCV和HBV标志物阳性率与ALT升高次数之间存在良好相关性。