Tushmalova N A
Zh Vyssh Nerv Deiat Im I P Pavlova. 1994 Jan-Feb;44(1):3-7.
Possibility of interpretation of the effects of psychotropic drugs on memory is considered from the viewpoint of general biological conception on molecular mechanisms of memory. Previous studies of functional-molecular mechanisms of memory in animals at different evolutionary levels, carried out by the author and collaborates, became a theoretical basis of the hypothesis proposed. In particular, genome modification was established to be induced by learning and specific and universal components of memory were revealed. Possibility of genome activation in the brain is considered as one of deciding factors in the mechanism of memory optimization by psychotropic drugs.
从关于记忆分子机制的一般生物学概念的角度考虑精神药物对记忆影响的解释可能性。作者及其合作者此前对不同进化水平动物记忆的功能分子机制进行的研究,成为了所提出假设的理论基础。特别是,已证实学习可诱导基因组修饰,并揭示了记忆的特定和普遍成分。大脑中基因组激活的可能性被视为精神药物优化记忆机制的决定性因素之一。