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Transcription and nucleotide excision repair--reflections, considerations and recent biochemical insights.

作者信息

Friedberg E C, Bardwell A J, Bardwell L, Wang Z, Dianov G

机构信息

Department of Pathology, University of Texas Southwestern Medical Center, Dallas 75235.

出版信息

Mutat Res. 1994 May 1;307(1):5-14. doi: 10.1016/0027-5107(94)90272-0.

DOI:10.1016/0027-5107(94)90272-0
PMID:7513823
Abstract

Recent years have witnessed considerable progress in the definition of the preferential repair of actively transcribed genes. Equally impressive progress has been achieved in our understanding of the genetic and biochemical complexity of the DNA-repair process called nucleotide excision repair (NER). Most recently studies in several laboratories have yielded observations which provide insights about how the processes of transcription and NER may be linked in prokaryotic and eukaryotic cells.

摘要

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Transcription and nucleotide excision repair--reflections, considerations and recent biochemical insights.
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2
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3
The human CSB (ERCC6) gene corrects the transcription-coupled repair defect in the CHO cell mutant UV61.
人类CSB(ERCC6)基因可纠正CHO细胞突变体UV61中的转录偶联修复缺陷。
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4
DNA repair domains within a human gene: selective repair of sequences near the transcription initiation site.人类基因中的DNA修复结构域:转录起始位点附近序列的选择性修复
EMBO J. 1996 Feb 1;15(3):675-83.
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