评估单克隆抗血型糖蛋白B作为一种不寻常的抗-S。
Evaluation of monoclonal anti-glycophorin B as an unusual anti-S.
作者信息
Hemming N J, Reid M E
机构信息
International Blood Group Reference Laboratory, SW Regional Transfusion Centre, Bristol, UK.
出版信息
Transfusion. 1994 Apr;34(4):333-6. doi: 10.1046/j.1537-2995.1994.34494233582.x.
BACKGROUND
Monoclonal antibody 148 is a murine monoclonal anti-glycophorin B that preferentially reacts with S+ human red cells.
STUDY DESIGN AND METHODS
Serologic and immunochemical studies were performed using red cells with various phenotypes.
RESULTS
These studies reveal that this monoclonal antibody is unusual in that it fails to agglutinate S+ TSEN+ red cells and agglutinates S- St(a+) and S- Dantu+ red cells.
CONCLUSION
These results allow the prediction of the glycophorin composition of GP.Hop (Mi.IV) red cells.
背景
单克隆抗体148是一种鼠单克隆抗血型糖蛋白B抗体，优先与S+人类红细胞发生反应。
研究设计与方法
使用具有不同表型的红细胞进行血清学和免疫化学研究。
结果
这些研究表明，这种单克隆抗体不同寻常，因为它不能凝集S+ TSEN+红细胞，却能凝集S- St(a+)和S- Dantu+红细胞。
结论
这些结果有助于预测GP.Hop（Mi.IV）红细胞的血型糖蛋白组成。
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