Warren D W, Walker J C, Drake A F, Lutz R W
Craniofacial Center, University of North Carolina, Chapel Hill 27599.
Laryngoscope. 1994 May;104(5 Pt 1):623-6. doi: 10.1002/lary.5541040517.
A technique that combines psychophysical measurements with continuous recording of nasal patency and respiratory behavior was used to study the psychophysical and respiratory responses of 10 subjects to well-controlled stimulation with three compounds differing in relative stimulatory effectiveness for nasal olfactory and trigeminal chemoreceptors. All four concentrations of acetic acid, amyl acetate, and phenethyl alcohol were well above the odor detection threshold. The magnitudes of both the increase in odor strength and nasal irritation and the decreases in tidal volume were greatest for acetic acid and least for phenethyl alcohol. Among the odorants, differences in nasal irritation were greater than those in odor strength, and tidal volume appeared to have a reasonably close and inverse relationship to nasal irritation.
一种将心理物理学测量与鼻腔通畅度和呼吸行为的连续记录相结合的技术，被用于研究10名受试者对三种对鼻腔嗅觉和三叉神经化学感受器具有不同相对刺激效果的化合物进行良好控制刺激时的心理物理和呼吸反应。醋酸、醋酸戊酯和苯乙醇的所有四种浓度均远高于气味检测阈值。醋酸引起的气味强度增加和鼻腔刺激程度以及潮气量的减少幅度最大，而苯乙醇引起的上述变化最小。在这些气味剂中，鼻腔刺激的差异大于气味强度的差异，并且潮气量似乎与鼻腔刺激存在合理的紧密反比关系。
