Nolan G H, Nahavandi M, Edwards C H, Knight E M, Johnson A A, Oyemade U J, Cole O J, Westney O E, Westney L S, Winborne D
College of Allied Health Sciences, Howard University, Washington, D.C. 20059.
J Nutr. 1994 Jun;124(6 Suppl):1022S-1027S. doi: 10.1093/jn/124.suppl_6.1022S.
Placenta from uncomplicated term pregnancies resulting in the birth of male infants weighing between 2900 and 3800 grams were analyzed for deoxyribonucleic acid (DNA), ribonucleic acid (RNA), and protein content. The mothers of the infants all had pre-pregnancy weights within +/- 15 percent expected body weight for body frame, according to the Metropolitan Life Tables. There were no significant differences, as regards the content of DNA, RNA and protein, between the placental cotyledons. Nine placenta from mothers giving birth to growth retarded infants were analyzed along with the placenta from six mothers with insulin dependent diabetes mellitus. A trend suggesting less DNA in the placenta of the severely growth retarded (symmetric) infants when compared with placenta from the normal pregnancies was not noted in the less severely growth retarded (asymmetric) infants. The placenta from the infants of diabetic pregnancies contained DNA and RNA in amounts similar to that found in normal pregnancy placenta but the protein content was greater.
对妊娠足月、分娩出体重在2900至3800克之间男婴的无并发症胎盘进行了脱氧核糖核酸（DNA）、核糖核酸（RNA）和蛋白质含量分析。根据大都会人寿表，这些婴儿的母亲孕前体重均在其体型预期体重的±15%范围内。胎盘小叶之间的DNA、RNA和蛋白质含量无显著差异。对9例分娩出生长受限婴儿的母亲的胎盘以及6例胰岛素依赖型糖尿病母亲的胎盘进行了分析。与正常妊娠胎盘相比，重度生长受限（对称型）婴儿的胎盘DNA含量有减少趋势，但在轻度生长受限（不对称型）婴儿中未观察到这一现象。糖尿病妊娠婴儿的胎盘所含DNA和RNA量与正常妊娠胎盘相似，但蛋白质含量更高。
