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经尿道微波热疗治疗单纯性良性前列腺增生。一项侧重于症状改善和并发症的前瞻性研究。

Transurethral microwave thermotherapy for uncomplicated benign prostatic hyperplasia. A prospective study with emphasis on symptomatic improvement and complications.

作者信息

Marteinsson V T, Due J

机构信息

Department of Surgery, University Hospital, Tromsø, Norway.

出版信息

Scand J Urol Nephrol. 1994 Mar;28(1):83-9. doi: 10.3109/00365599409180476.

DOI:10.3109/00365599409180476
PMID:7516577
Abstract

A single session of transurethral microwave thermotherapy (TUMT) was used in 115 patients with symptomatic uncomplicated benign prostatic hyperplasia (BPH). Subjective symptoms and urodynamic parameters were assessed before treatment, at 6 weeks, 3, 6 and 12 months after treatment and complications recorded. There was significant improvement in obstructive, irritative and total symptom scores at all time intervals. The maximum and corrected flow rate improved significantly at all time intervals as well as the decrease in residual urine. Complications occurred in 45.2% patients with no mortality. The most frequent complications were urinary tract infection (32.1%) and urinary retention (28.6%). Two patients experienced retrograde ejaculation. No patient was hospitalized due to complication. Four (3.5%) patients required transurethral resection of the prostate during the follow-up period due to persistent symptoms; 96.5% have remained satisfied. In conclusion, TUMT is a promising treatment option in selected patients with BPH, is well tolerated and complications are easy to treat. Its main advantage is the fact that it can be administered on an outpatient basis, thus reducing patient inconvenience and costs.

摘要

115例有症状的单纯性良性前列腺增生(BPH)患者接受了单次经尿道微波热疗(TUMT)。在治疗前、治疗后6周、3个月、6个月和12个月评估主观症状和尿动力学参数,并记录并发症。在所有时间点,梗阻性、刺激性和总症状评分均有显著改善。最大尿流率和校正尿流率在所有时间点均显著改善,残余尿量也减少。45.2%的患者出现并发症,无死亡病例。最常见的并发症是尿路感染(32.1%)和尿潴留(28.6%)。2例患者出现逆行射精。无患者因并发症住院。4例(3.5%)患者在随访期间因症状持续需要行经尿道前列腺切除术;96.5%的患者仍感满意。总之,TUMT是选定的BPH患者的一种有前景的治疗选择,耐受性良好,并发症易于治疗。其主要优点是可以在门诊进行,从而减少患者的不便和费用。

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引用本文的文献

1
Transurethral microwave thermotherapy in benign prostatic hyperplasia.
Curr Urol Rep. 2000 Aug;1(2):110-5. doi: 10.1007/s11934-000-0045-x.
2
Changing therapeutic regimens in benign prostatic hyperplasia. Clinical and economic considerations.良性前列腺增生治疗方案的变更:临床与经济考量
Pharmacoeconomics. 2001;19(2):131-53. doi: 10.2165/00019053-200119020-00003.