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经尿道微波热疗与经尿道前列腺切除术治疗症状性良性前列腺梗阻的前瞻性随机研究:一项为期2年的随访研究

Transurethral microwave thermotherapy versus transurethral resection for symptomatic benign prostatic obstruction: a prospective randomized study with a 2-year follow-up.

作者信息

Dahlstrand C, Waldén M, Geirsson G, Pettersson S

机构信息

Department of Urology, Sahlgrenska University Hospital, Göteborg, Sweden.

出版信息

Br J Urol. 1995 Nov;76(5):614-8. doi: 10.1111/j.1464-410x.1995.tb07788.x.

Abstract

OBJECTIVE

To compare the outcome of transurethral resection of the prostate (TURP) and transurethral microwave thermotherapy (TUMT) on symptomatic benign prostatic hyperplasia (BPH).

PATIENTS AND METHODS

Patients with symptomatic BPH were treated by either TURP (32 patients; mean age 70 +/- 6 years) or TUMT (37 patients; mean age 67 +/- 9 years) and assessed using the Madsen-Iversen symptom score, measurements of urinary free flow rate and post-void residual urine volume, digital rectal examination, transrectal ultrasonography, cystometry and pressure-flow measurement, ultrasonography or intravenous pyelography (IVP) of the upper urinary tract, urine analysis and routine blood chemistry including serum prostate-specific antigen (PSA) level. Examinations were repeated at fixed intervals for up to 24 months after treatment.

RESULTS

After both TURP and TUMT there was an improvement in symptom score, residual urine volume, free flow rate and infravesical obstruction. The improvements of free flow rate and obstruction were more pronounced after TURP. Serious complications, such as bleeding requiring a re-operation, occurred only in patients who underwent TURP.

CONCLUSION

Satisfactory results were obtained after both treatments and the improvements with either treatment lasted for at least 24 months.

摘要

目的

比较经尿道前列腺电切术(TURP)和经尿道微波热疗(TUMT)治疗症状性良性前列腺增生(BPH)的疗效。

患者与方法

对症状性BPH患者分别采用TURP(32例,平均年龄70±6岁)或TUMT(37例,平均年龄67±9岁)进行治疗,并使用马德森-艾弗森症状评分、尿流率测量、排尿后残余尿量测量、直肠指检、经直肠超声检查、膀胱测压和压力-流率测定、上尿路超声检查或静脉肾盂造影(IVP)、尿液分析以及包括血清前列腺特异性抗原(PSA)水平在内的常规血液生化检查进行评估。治疗后每隔固定时间重复检查,最长至24个月。

结果

TURP和TUMT治疗后症状评分、残余尿量、尿流率及膀胱颈梗阻均有改善。TURP术后尿流率和梗阻的改善更为明显。严重并发症,如需要再次手术的出血,仅发生在接受TURP治疗的患者中。

结论

两种治疗均取得了满意的效果,且两种治疗的改善效果至少持续24个月。

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