Abildskov J A, Lux R L
Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City 84112.
Pacing Clin Electrophysiol. 1994 May;17(5 Pt 1):944-52. doi: 10.1111/j.1540-8159.1994.tb01437.x.
Spiral excitation fronts have been demonstrated in association with reentry in a computer model of propagated excitation. Fronts were initiated by the reentrant circuits but the spiral configurations themselves occurred outside the circuits. Excitation initiated near the initial portion of reentrant circuits propagated greater distances during a particular time period than excitation initiated from later portions of the circuit. This resulted in spiral configuration of excitation fronts in which the front was located at increasing distance from the latest initiating event. Excitation fronts that did not themselves have spiral configurations in certain matrices were identifiable as parts of spiral configurations that occurred when the same reentrant events were present in other matrices. Spiral waves were initiated by either leading circle reentry associated with functional block to propagation or reentry associated with structural obstacles. They also occurred in the presence of initially uniform refractory periods and resulted in self-sustained reentrant excitation. This however, required particular conditions of excitation such that recovery times constituted a functional block permitting leading circle reentry.
在传播性兴奋的计算机模型中，螺旋状兴奋波前已被证明与折返相关。波前由折返环路引发，但螺旋结构本身出现在环路之外。在特定时间段内，在折返环路起始部分附近引发的兴奋比从环路较后部分引发的兴奋传播得更远。这导致了兴奋波前的螺旋状结构，其中波前与最新引发事件的距离越来越远。在某些基质中本身没有螺旋结构的兴奋波前，当相同的折返事件出现在其他基质中时，可被识别为螺旋结构的一部分。螺旋波由与功能性传导阻滞相关的领先环折返或与结构性障碍相关的折返引发。它们也在初始均匀不应期存在的情况下出现，并导致自持性折返兴奋。然而，这需要特定的兴奋条件，使得恢复时间构成允许领先环折返的功能性传导阻滞。
