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总结:RNA的修饰核苷。

Summary: the modified nucleosides of RNA.

作者信息

Limbach P A, Crain P F, McCloskey J A

机构信息

Department of Medicinal Chemistry, University of Utah, Salt Lake City 84112.

出版信息

Nucleic Acids Res. 1994 Jun 25;22(12):2183-96. doi: 10.1093/nar/22.12.2183.

DOI:10.1093/nar/22.12.2183
PMID:7518580
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC523672/
Abstract

A comprehensive listing is made of posttranscriptionally modified nucleosides from RNA reported in the literature through mid-1994. Included are chemical structures, common names, symbols, Chemical Abstracts registry numbers (for ribonucleoside and corresponding base), Chemical Abstracts Index Name, phylogenetic sources, and initial literature citations for structural characterization or occurrence, and for chemical synthesis. The listing is categorized by type of RNA: tRNA, rRNA, mRNA, snRNA, and other RNAs. A total of 93 different modified nucleosides have been reported in RNA, with the largest number and greatest structural diversity in tRNA, 79; and 28 in rRNA, 12 in mRNA, 11 in snRNA and 3 in other small RNAs.

摘要

本文全面列举了截至1994年年中文献报道的RNA转录后修饰核苷。内容包括化学结构、通用名称、符号、化学文摘登记号(针对核糖核苷及相应碱基)、化学文摘索引名称、系统发生来源,以及结构表征或存在情况、化学合成的初始文献引用。该列表按RNA类型分类:tRNA、rRNA、mRNA、snRNA和其他RNA。RNA中共报道了93种不同的修饰核苷,其中tRNA中的数量最多且结构多样性最大,有79种;rRNA中有28种,mRNA中有12种,snRNA中有11种,其他小RNA中有3种。

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