Murakami Y, Ohshima K, Mochizuki T, Yanaihara N
Clinic of Endocrine Diseases, Shizuoka City Hospital, Japan.
J Clin Endocrinol Metab. 1993 Nov;77(5):1436-8. doi: 10.1210/jcem.77.5.7521348.
Galanin is a brain-gut peptide occurring widely in the central and peripheral nervous system. Effects of iv administration of synthetic human galanin on pituitary GH, PRL, and antidiuretic hormone secretion were studied. Intravenous infusion of the peptide resulted in a significant increase in plasma GH levels whereas PRL and antidiuretic hormone did not significantly change. These findings suggest that galanin might play a role in modulating GH secretion in humans.
甘丙肽是一种广泛存在于中枢和外周神经系统的脑肠肽。研究了静脉注射合成人甘丙肽对垂体生长激素(GH)、催乳素(PRL)和抗利尿激素分泌的影响。静脉输注该肽导致血浆GH水平显著升高,而PRL和抗利尿激素没有显著变化。这些发现表明甘丙肽可能在调节人类GH分泌中起作用。