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Prediction of an HLA-B44 binding motif by the alignment of known epitopes and molecular modeling of the antigen binding cleft.

作者信息

Thorpe C J, Travers P J

机构信息

Laboratory of Molecular Biology, Bloomsbury Molecular Recognition Centre, London, England.

出版信息

Immunogenetics. 1994;40(4):303-5. doi: 10.1007/BF00189977.

DOI:10.1007/BF00189977
PMID:7521859
Abstract
摘要

相似文献

1
Prediction of an HLA-B44 binding motif by the alignment of known epitopes and molecular modeling of the antigen binding cleft.
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2
Identification of the peptide binding motif for HLA-B44, one of the most common HLA-B alleles in the Caucasian population.鉴定HLA - B44的肽结合基序,HLA - B44是白种人群中最常见的HLA - B等位基因之一。
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Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition.人类白细胞抗原中的自然微多态性为抗原识别的遗传控制提供了基础。
J Exp Med. 2009 Jan 16;206(1):209-19. doi: 10.1084/jem.20082136. Epub 2009 Jan 12.
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Different HLA-B27 subtypes present the same immunodominant Epstein-Barr virus peptide.不同的HLA - B27亚型呈现相同的免疫显性爱泼斯坦 - 巴尔病毒肽。
J Exp Med. 1993 Sep 1;178(3):879-87. doi: 10.1084/jem.178.3.879.
6
Five new cytotoxic T cell epitopes identified within Epstein-Barr virus nuclear antigen 3.在爱泼斯坦-巴尔病毒核抗原3中鉴定出五个新的细胞毒性T细胞表位。
J Gen Virol. 1994 Sep;75 ( Pt 9):2489-93. doi: 10.1099/0022-1317-75-9-2489.
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Assessment of major histocompatibility complex class I interaction with Epstein-Barr virus and human immunodeficiency virus peptides by elevation of membrane H-2 and HLA in peptide loading-deficient cells.通过提高肽负载缺陷细胞中膜H-2和HLA水平评估主要组织相容性复合体I类与爱泼斯坦-巴尔病毒和人类免疫缺陷病毒肽的相互作用。
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The life span of major histocompatibility complex-peptide complexes influences the efficiency of presentation and immunogenicity of two class I-restricted cytotoxic T lymphocyte epitopes in the Epstein-Barr virus nuclear antigen 4.主要组织相容性复合体-肽复合物的寿命影响了爱泼斯坦-巴尔病毒核抗原4中两个I类限制性细胞毒性T淋巴细胞表位的呈递效率和免疫原性。
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Characterization of natural peptide ligands for HLA-B*4402 and -B*4403: implications for peptide involvement in allorecognition of a single amino acid change in the HLA-B44 heavy chain.HLA-B*4402和-B*4403天然肽配体的表征:肽参与HLA-B44重链单个氨基酸变化的同种异体识别的意义。
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HLA-binding regions of HIV-1 proteins. I. Detection of seven HLA binding regions in the HIV-1 Nef protein.HIV-1蛋白的HLA结合区域。I. HIV-1 Nef蛋白中七个HLA结合区域的检测。
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引用本文的文献

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Binding of gluten-derived peptides to the HLA-DQ2 (alpha1*0501, beta1*0201) molecule, assessed in a cellular assay.通过细胞试验评估麸质衍生肽与HLA-DQ2(α1*0501,β1*0201)分子的结合情况。
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2
Definition of the HLA-A29 peptide ligand motif allows prediction of potential T-cell epitopes from the retinal soluble antigen, a candidate autoantigen in birdshot retinopathy.HLA-A29肽配体基序的定义有助于从视网膜可溶性抗原预测潜在的T细胞表位,视网膜可溶性抗原是鸟枪样视网膜病变中的一种候选自身抗原。
Proc Natl Acad Sci U S A. 1996 Apr 16;93(8):3466-70. doi: 10.1073/pnas.93.8.3466.
3

本文引用的文献

1
Peptide selection by class I molecules of the major histocompatibility complex.主要组织相容性复合体I类分子对肽段的选择
Curr Biol. 1993 Dec 1;3(12):854-66. doi: 10.1016/0960-9822(93)90219-e.
2
Peptide motifs of HLA-B35 and -B37 molecules.HLA - B35和 - B37分子的肽基序
Immunogenetics. 1993;38(2):161-2. doi: 10.1007/BF00190906.
3
Peptides naturally presented by MHC class I molecules.由MHC I类分子天然呈递的肽段。
Analysis of naturally processed human histocompatibility leukocyte antigen class I-bound peptides from hepatocellular carcinoma tissues in vivo.
体内肝细胞癌组织中天然加工的人类组织相容性白细胞抗原I类结合肽的分析
Jpn J Cancer Res. 1995 Oct;86(10):962-8. doi: 10.1111/j.1349-7006.1995.tb03008.x.
Annu Rev Immunol. 1993;11:213-44. doi: 10.1146/annurev.iy.11.040193.001241.
4
Naturally processed HLA class I bound peptides from c-myc-transfected cells reveal allele-specific motifs.来自c-myc转染细胞的天然加工的HLA I类结合肽揭示了等位基因特异性基序。
J Immunol. 1993 Dec 1;151(11):5966-74.
5
Dominant aromatic/aliphatic C-terminal anchor in HLA-B*2702 and B*2705 peptide motifs.HLA-B*2702和B*2705肽基序中占主导地位的芳香族/脂肪族C末端锚定序列。
Immunogenetics. 1994;39(1):74-7. doi: 10.1007/BF00171803.
6
Gag-specific cytotoxic T lymphocytes from human immunodeficiency virus type 1-infected individuals: Gag epitopes are clustered in three regions of the p24gag protein.来自1型人类免疫缺陷病毒感染个体的Gag特异性细胞毒性T淋巴细胞:Gag表位聚集在p24gag蛋白的三个区域。
J Virol. 1993 Feb;67(2):694-702. doi: 10.1128/JVI.67.2.694-702.1993.
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Antigen recognition by class I-restricted T lymphocytes.I类限制性T淋巴细胞的抗原识别
Annu Rev Immunol. 1989;7:601-24. doi: 10.1146/annurev.iy.07.040189.003125.
8
The structure of HLA-B27 reveals nonamer self-peptides bound in an extended conformation.HLA - B27的结构显示出以延伸构象结合的九聚体自身肽。
Nature. 1991 Sep 26;353(6342):321-5. doi: 10.1038/353321a0.
9
Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules.
Nature. 1991 May 23;351(6324):290-6. doi: 10.1038/351290a0.
10
An Epstein-Barr virus-specific cytotoxic T-cell epitope present on A- and B-type transformants.存在于A 型和 B 型转化体上的一种爱泼斯坦-巴尔病毒特异性细胞毒性 T 细胞表位。
J Virol. 1990 Aug;64(8):3974-6. doi: 10.1128/JVI.64.8.3974-3976.1990.