Lü Y, Ding Y Q, Qin B Z, Li J S
Department of Anatomy, Fourth Military Medical University, Xi'an, People's Republic of China.
Neurosci Lett. 1994 Apr 25;171(1-2):70-2. doi: 10.1016/0304-3940(94)90607-6.
The distribution and origin of axon terminals containing nitric oxide synthase (NOS) were examined in the nucleus of the solitary tract (NST) of the rat by NADPH diaphorase histochemistry combined with nodose ganglionectomy. Axon terminals with NADPH diaphorase activity were densely distributed in the middle and caudal part of the NST. After removal of the nodose ganglion (NG), most of the axon terminals with NADPH activity in the NST were eliminated on the ipsilateral side. These results indicated that most of the axon terminals with NADPH diaphorase in the NST derive from the primary afferent neurons in the NG, and that NOS may be richly contained in the central terminals of NG neurons to produce nitric oxide as a transmitter.
通过将烟酰胺腺嘌呤二核苷酸磷酸黄递酶组织化学与结状神经节切除术相结合，研究了大鼠孤束核（NST）中含一氧化氮合酶（NOS）的轴突终末的分布和起源。具有烟酰胺腺嘌呤二核苷酸磷酸黄递酶活性的轴突终末密集分布于NST的中、尾段。切除结状神经节（NG）后，NST中大部分具有烟酰胺腺嘌呤二核苷酸活性的轴突终末在同侧被消除。这些结果表明，NST中大部分具有烟酰胺腺嘌呤二核苷酸磷酸黄递酶的轴突终末来源于NG中的初级传入神经元，并且NOS可能大量存在于NG神经元的中枢终末中，以产生一氧化氮作为神经递质。
