Kroiss A, Peschl L, Schüller J, Benko H, Neumayr A
Acta Med Austriaca. 1978;5(3):103-5.
In portosystemic shunt surgery, there still is a lack of correlation between various preoperative hemodynamic measurements and the postoperative clinical course of patients. The magnitude of post-shunt increment in hepatic arterial flow was found to be directly related to long term prognosis. To predict the arterial response for selecting patients for shunting, we tried to use a new non invasive method: Arterial and portal components of total liver blood flow were determined quantitatively by "Sequential hepato-splenic scintigraphy". Dilatation capability of the hepatic artery, was tested by means of the hemodynamic action of Parathyroid hormone (PH). PH has been found to induce a large and exclusive augmentation of hepatic arterial blood flow. We were able to document a statistically highly significant increase in hepatic arterial flow following i. v. applications of PH. The extent of arterial increment appears to be dependent upon the degree of entrapment of the hepatic arterioles by the fibrous tissues of cirrhosis.
在门体分流手术中，术前各种血流动力学测量值与患者术后临床病程之间仍然缺乏相关性。发现分流术后肝动脉血流增加的幅度与长期预后直接相关。为了预测动脉反应以选择适合分流的患者，我们尝试使用一种新的非侵入性方法：通过“序贯肝脾闪烁显像术”定量测定肝脏总血流量的动脉和门静脉成分。通过甲状旁腺激素（PH）的血流动力学作用来测试肝动脉的扩张能力。已发现PH可引起肝动脉血流量的大幅且唯一增加。我们能够证明静脉注射PH后肝动脉血流有统计学上高度显著的增加。动脉增加的程度似乎取决于肝硬化纤维组织对肝小动脉的压迫程度。
