Gale R P, Caligaris-Cappio F, Dighiero G, Keating M, Montserrat E, Rai K
Salick Health Care Inc, Los Angeles, CA.
Leukemia. 1994 Sep;8(9):1610-4.
The data we discuss indicate substantial recent progress in understanding and treating CLL. However, despite considerable new information, many of the intriguing issues we posed at previous IWCLL meetings remain unanswered. Prominent among these are the questions of what causes CLL, what is the relation between CLL and normal B-cell development, are T-cell abnormalities a cause of consequence of CLL, why are auto-immune features so prominent and how is CLL best treated? Although these gaps in our knowledge are unfortunate, they give us the opportunity for yet another IWCLL meeting: 1996 in Greece. More to follow.
我们所讨论的数据表明,近期在慢性淋巴细胞白血病(CLL)的认识和治疗方面取得了重大进展。然而,尽管有大量新信息,但我们在以往国际慢性淋巴细胞白血病研讨会(IWCLL)上提出的许多有趣问题仍未得到解答。其中突出的问题包括:CLL的病因是什么?CLL与正常B细胞发育之间有何关系?T细胞异常是CLL的原因还是结果?为什么自身免疫特征如此突出?以及CLL的最佳治疗方法是什么?尽管我们知识上的这些空白令人遗憾,但它们为我们举办另一次IWCLL会议提供了契机:1996年在希腊召开。更多内容随后奉上。