Effects of B subunit of cholera toxin on histamine release from rat peritoneal mast cells.
作者信息
Sugimoto K, Kasuga F, Kumagai S
机构信息
Department of Biomedical Food Research, National Institute of Health, Tokyo, Japan.
出版信息
Int Arch Allergy Immunol. 1994 Oct;105(2):195-7. doi: 10.1159/000236825.
PMID:7522688
Abstract
We studied the effects of B subunit of cholera toxin (CTB) on secretagogue-induced histamine release from rat peritoneal mast cells. CTB inhibited the release of histamine in response to compound 48/80, but not in response to mastoparan, substance P, concanavalin A or ionophore A23187. The results suggest that CTB can be used as a tool for studying the cellular events involved in histamine release from mast cells.
摘要
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