编码大西洋鲑鱼α1-微球蛋白/比库宁蛋白的cDNA克隆序列。
Sequence of a cDNA clone encoding the Atlantic salmon alpha 1-microglobulin/bikunin protein.
作者信息
Hanley S, Powell R
机构信息
Department of Microbiology, University College, Galway, Ireland.
出版信息
Gene. 1994 Sep 30;147(2):297-8. doi: 10.1016/0378-1119(94)90086-8.
PMID:7523247
Abstract
We report here the nucleotide sequence of a cDNA clone encoding the salmon (Salmo salar) alpha 1-microglobulin/bikunin precursor protein (sAMBP). The encoded precursor shows 36 and 42% amino acid (aa) similarity to the AMBP of pig and human, respectively. Signature aa motifs are conserved. The data infer that the ancestral AMBP gene arose more than 450 million years ago, before the tetrapod-fish divergence.
摘要
我们在此报告一个编码鲑鱼（Salmo salar）α1-微球蛋白/抑肽酶前体蛋白（sAMBP）的cDNA克隆的核苷酸序列。所编码的前体分别与猪和人的AMBP具有36%和42%的氨基酸（aa）相似性。标志性氨基酸基序是保守的。数据推断，AMBP基因的祖先出现在4.5亿多年前，即四足动物与鱼类分化之前。
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