Turnbull A D, Gundy E, Howland W S, Beattie E J
Clin Bull. 1978;8(4):139-42.
The overall surgical mortality rate of 3.4 percent in 32,308 operations (22,288 patients) between 1970 and 1974 was essentially the same as the 3.7 percent recorded for 30,241 operations (22,967 patients) during the preceding 5 years. The surgical mortality rate among patients 70 years or older fell significantly (p less than 0.005) from 6.8 percent of 3,754 procedures (2,766 patients) during the 1965--1969 period to 4.8 percent of 4,050 procedures (2, 783 patients) between 1970 and 1974. There was a 50 percent increase in operative mortality from all causes among the elderly when compared to the rates of 4.7 percent of patients and 3.2 percent of procedures observed in patients under the age of 70. If the patients in whom the surgical procedure seemed incidental to their death from other causes are excluded, the mortality rate among the elderly was a more realistic 2.8 percent of procedures (114 patients) between 1970 and 1974. The 30-day mortality rate from all causes noted in this group was 3.7 percent of procedures, or 5.4 percent of patients. These results appear to justify the philosophy that age alone is no contraindication to potentially curative cancer surgery, and demonstrate that such surgery can be performed with acceptable mortality rates.
1970年至1974年间,32308例手术(涉及22288名患者)的总体手术死亡率为3.4%,这与前5年30241例手术(涉及22967名患者)记录的3.7%基本相同。70岁及以上患者的手术死亡率显著下降(p小于0.005),从1965 - 1969年期间3754例手术(涉及2766名患者)的6.8%降至1970年至1974年间4050例手术(涉及2783名患者)的4.8%。与70岁以下患者4.7%的患者死亡率和3.2%的手术死亡率相比,老年人所有原因导致的手术死亡率增加了50%。如果排除那些手术似乎是因其他原因死亡的附带情况的患者,1970年至1974年间老年人的死亡率更实际,为手术的2.8%(114名患者)。该组中记录的所有原因导致的30天死亡率为手术的3.7%,或患者的5.4%。这些结果似乎证明了仅年龄本身并非潜在治愈性癌症手术的禁忌这一理念是合理的,并表明这种手术可以在可接受的死亡率下进行。