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内镜逆行胰胆管造影术联合腹腔镜胆囊切除术在胆总管结石治疗中的作用。

The role of endoscopic retrograde cholangiopancreatography with laparoscopic cholecystectomy in the management of choledocholithiasis.

作者信息

Cisek P L, Greaney G C

机构信息

Santa Barbara Cottage Hospital, CA 93102.

出版信息

Am Surg. 1994 Oct;60(10):772-6.

PMID:7524385
Abstract

Perioperative endoscopic retrograde cholangiopancreatography (ERCP) and sphincterotomy (ES) offer the ability to remove common bile duct stones (CBDS) and still use the laparoscopic technique for cholecystectomy. The accuracy of predicting choledocholithiasis has been variable in several studies. The indications and complications of perioperative ERCP and ES with laparoscopic cholecystectomy (LC) are presented here. Between 6/1/90 and 11/11/93, 484 LC were performed at Santa Barbara Cottage Hospital. A total of 38 patients underwent perioperative ERCP; 33 patients underwent preoperative ERCP with 3/33 (9%) failing to cannulate the ampulla; 15 patients had choledocholithiasis; and 14/15 (93%) were cleared by ES. Fifteen patients had a normal CBD on ERCP. There were no deaths in this group of patients, seven of 38 (18%) had complications, including bleeding and post ERCP hyperamylasemia. Patients who had a normal CBD and underwent preoperative ERCP (9/15, 60%) had a history of gallstone pancreatitis or hyperamylasemia that was resolved or resolving before ERCP. Patients without stones on ERCP or cholangiogram (11/15, 73%) had a normal bilirubin (avg. 1.0 mg/dL; Range 0.4-2.3). Patients with choledocholithiasis (8/15, 53%) had a history of jaundice or elevated bilirubin before ERCP (avg. 2.59 mg/dL; range 0.2-9.3). ERCP with ES and laparoscopic cholecystectomy is a safe and effective method for the management of symptomatic cholelithiasis with choledocholithiasis. A history of gallstone pancreatitis or hyperamylasemia that is resolving or resolved in the absence of an elevated bilirubin does not require preoperative ERCP before LC with cholangiogram.

摘要

围手术期内镜逆行胰胆管造影术(ERCP)和括约肌切开术(ES)能够去除胆总管结石(CBDS),并且仍可采用腹腔镜技术进行胆囊切除术。在多项研究中,预测胆总管结石的准确性各不相同。本文介绍了围手术期ERCP和ES联合腹腔镜胆囊切除术(LC)的适应证及并发症。1990年6月1日至1993年11月11日期间,圣巴巴拉 Cottage 医院共进行了484例LC手术。共有38例患者接受了围手术期ERCP;33例患者接受了术前ERCP,其中3/33(9%)未能成功插管至壶腹;15例患者患有胆总管结石;14/15(93%)通过ES清除结石。15例患者ERCP显示胆总管正常。该组患者无死亡病例,38例中有7例(18%)出现并发症,包括出血和ERCP术后高淀粉酶血症。胆总管正常且接受术前ERCP的患者(9/15,60%)有胆石性胰腺炎或高淀粉酶血症病史,在ERCP前已缓解或正在缓解。ERCP或胆管造影未发现结石的患者(11/15,73%)胆红素正常(平均1.0mg/dL;范围0.4 - 2.3)。患有胆总管结石的患者(8/15,53%)在ERCP前有黄疸或胆红素升高病史(平均2.59mg/dL;范围0.2 - 9.3)。ERCP联合ES及腹腔镜胆囊切除术是治疗有症状胆石症合并胆总管结石的一种安全有效的方法。在无胆红素升高的情况下,正在缓解或已缓解的胆石性胰腺炎或高淀粉酶血症病史患者,在进行LC联合胆管造影术前不需要进行术前ERCP。

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