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粒细胞集落刺激因子治疗期间的髓外造血

Extramedullary hematopoiesis during therapy with granulocyte colony-stimulating factor.

作者信息

Redmond J, Kantor R S, Auerbach H E, Spiritos M D, Moore J T

机构信息

Department of Medicine, Abington Memorial Hospital, PA 19001.

出版信息

Arch Pathol Lab Med. 1994 Oct;118(10):1014-5.

PMID:7524465
Abstract

Granulocyte colony-stimulating factor is a glycoprotein that promotes the proliferation and differentiation of neutrophils. It also results in an increase in circulating hematopoietic progenitor cells. We describe two cases of extramedullary hematopoiesis in patients receiving granulocyte colony-stimulating factor with chemotherapy for metastatic breast cancer.

摘要

粒细胞集落刺激因子是一种糖蛋白,可促进中性粒细胞的增殖和分化。它还会导致循环造血祖细胞数量增加。我们描述了两例接受粒细胞集落刺激因子联合化疗治疗转移性乳腺癌的患者发生髓外造血的病例。

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