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丘脑双侧对称性软化。

Bilateral symmetrical softening of the thalamus.

作者信息

Szirmai I, Guseo A, Molnár M

出版信息

J Neurol. 1977 Dec 1;217(1):57-65. doi: 10.1007/BF00316317.

DOI:10.1007/BF00316317
PMID:75253
Abstract

The clinical and pathological data of a 48 year old patient who survived 40 days are reported. Her disturbance of consciousness corresponded to an apallic syndrome, which 12 days later bacame akinetic mutism. Symmetrical softening involving the medial thalamic nuclei from the plane of the corpora mamillaria to the red nuclei was found. The ischemic lesion might be explained by transient circulatory collapse combined with hypoplasia of the vertebrobasialr arteries. On the EEG slight irregular alpha activity was recorded (alpha coma) and external stimuli elicited theta-delta waves (paradox activation). A survey of the literature of akinetic mutism is included and the correlation between non-hypnoid unconsciousness and EEG is discussed.

摘要

报告了一名存活40天的48岁患者的临床和病理数据。她的意识障碍符合去大脑皮质综合征,12天后发展为运动不能性缄默症。发现从乳头体平面到红核的内侧丘脑核出现对称性软化。缺血性病变可能是由短暂性循环衰竭合并椎基底动脉发育不全所致。脑电图记录到轻微不规则的α活动(α昏迷),外部刺激诱发θ-δ波(反常激活)。文中还包括了对运动不能性缄默症文献的综述,并讨论了非类催眠性无意识与脑电图之间的相关性。

相似文献

1
Bilateral symmetrical softening of the thalamus.丘脑双侧对称性软化。
J Neurol. 1977 Dec 1;217(1):57-65. doi: 10.1007/BF00316317.
2
Akinetic mutism--not coma.运动不能性缄默症——而非昏迷。
Age Ageing. 2009 May;38(3):350-1. doi: 10.1093/ageing/afp005. Epub 2009 Mar 18.
3
[Akinetic mutism: bilateral multiple foci of encephalomalacia at the thalamus and basal nucleus].[运动不能性缄默症:丘脑和基底核双侧多发性脑软化灶]
Nihon Rinsho. 1975 Apr 10;Spec No:920-1, 1396-9.
4
[Akinetic mutism and bicingular softening. 3 anatomo-clinical cases].[运动不能性缄默症与双侧扣带回软化。3例解剖临床病例]
Rev Neurol (Paris). 1975 Feb;131(2):121-31.
5
Akinetic mutism and bilateral anterior cerebral artery occlusion.运动不能性缄默症与双侧大脑前动脉闭塞
J Neurol Neurosurg Psychiatry. 1971 Dec;34(6):693-8. doi: 10.1136/jnnp.34.6.693.
6
[CONSCIOUSNESS DISORDERS AND AKINETIC MUTISM. ANATOMO-CLINICAL STUDY OF A BILATERAL PARAMEDIAN SOFTENING OF THE CEREBRAL PEDUNCLE AND THALAMUS].[意识障碍与运动不能性缄默症。大脑脚和丘脑双侧旁正中软化的解剖临床研究]
Rev Neurol (Paris). 1963 Aug;109:115-31.
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[The syndrome of akinetic mutism and the symptom of whispering speech in acute disorders of cerebral circulation].[急性脑循环障碍中的运动不能性缄默综合征及低语症状]
Zh Nevropatol Psikhiatr Im S S Korsakova. 1972;72(4):507-10.
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BIPLEDs in akinetic mutism caused by bilateral anterior cerebral artery infarction.双侧大脑前动脉梗死所致运动不能性缄默症中的双向发光二极管。
Clin Neurophysiol. 2001 Sep;112(9):1726-8. doi: 10.1016/s1388-2457(01)00602-2.
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[Pallidonigral and thalamic degeneration. A contribution to thalamic dementia (author's transl)].
Arch Psychiatr Nervenkr (1970). 1974;219(4):323-30. doi: 10.1007/BF00343603.
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The syndrome(s) of akinetic mutism. Extent of the concept based on clinical, anatomical and physiopathological grounds.运动不能性缄默综合征。基于临床、解剖学和病理生理学依据的概念范围。
Int Surg. 1971 Dec;56(6):392-401.

引用本文的文献

1
Presentation of bilateral thalamic infarction on CT, MRI and PET.双侧丘脑梗死在CT、MRI和PET上的表现。
Neuroradiology. 1985;27(5):414-9. doi: 10.1007/BF00327605.
2
Diagnosis and treatment of deep cerebral vein thrombosis.
Neurosurg Rev. 1991;14(2):145-8. doi: 10.1007/BF00313042.
3
Bilateral reversible thalamic lesions on computed tomography.计算机断层扫描显示双侧可逆性丘脑病变。
Neuroradiology. 1979 Oct 31;18(4):201-4. doi: 10.1007/BF00345726.

本文引用的文献

1
Disturbances of consciousness with lesions of the brain-stem and diencephalon.伴有脑干和间脑病变的意识障碍
Brain. 1952 Jun;75(2):109-46. doi: 10.1093/brain/75.2.109.
2
Akinetic mutism: review of the literature and report of a case.运动不能性缄默症:文献综述及病例报告
J Nerv Ment Dis. 1961 Dec;133:536-53.
3
[THE PROTRACTED FORM OF POSTTRAUMATIC ENCEPHALOPATHY. CLINICOMORPHOLOGICAL FINDINGS AFTER SEVERE CLOSED CRANIOCEREBRAL TRAUMA WITH LONG SURVIVAL].[创伤后脑病的迁延形式。严重闭合性颅脑创伤长期存活后的临床形态学表现]
4
Chronic electrical stimulation of the thalamic unspecific activating system in a patient with coma due to midbrain and upper brain stem infarction.对一名因中脑和脑桥上部梗死导致昏迷的患者进行丘脑非特异性激活系统的慢性电刺激。
Acta Neurochir (Wien). 1979;47(3-4):235-44. doi: 10.1007/BF01406406.
Nervenarzt. 1963 Apr;34:145-59.
4
EEG PATTERN RESEMBLING WAKEFULNESS IN UNRESPONSIVE DECEREBRATE STATE FOLLOWING TRAUMATIC BRAIN-STEM INFARCT.创伤性脑干梗死致无反应性去大脑状态下类似觉醒的脑电图模式
Electroencephalogr Clin Neurophysiol. 1964 Mar;16:285-9. doi: 10.1016/0013-4694(64)90111-7.
5
[CONSCIOUSNESS DISORDERS AND AKINETIC MUTISM. ANATOMO-CLINICAL STUDY OF A BILATERAL PARAMEDIAN SOFTENING OF THE CEREBRAL PEDUNCLE AND THALAMUS].[意识障碍与运动不能性缄默症。大脑脚和丘脑双侧旁正中软化的解剖临床研究]
Rev Neurol (Paris). 1963 Aug;109:115-31.
6
THE ELECTROENCEPHALOGRAM IN ACUTE VASCULAR LESIONS OF THE BRAIN STEM AND THE CEREBELLUM.脑干和小脑急性血管性病变中的脑电图
Acta Neurol Scand. 1964;40(1):58-68. doi: 10.1111/j.1600-0404.1964.tb04266.x.
7
Electroencephalographic changes during the state of coma.昏迷状态下的脑电图变化。
Electroencephalogr Clin Neurophysiol. 1958 Nov;10(4):589-606. doi: 10.1016/0013-4694(58)90061-0.
8
[Prolonged hypersomnia caused by bilateral lesions of the medial activator system; thrombotic syndrome of the bifurcation of the basilar trunk].[内侧激活系统双侧病变所致的长期睡眠过多;基底动脉干分叉处血栓形成综合征]
Rev Neurol (Paris). 1958 Feb;98(2):117-33.
9
The electroencephalogram in brain stem vascular disease; some observations relating electroencephalographic findings to various combinations of infarction and vascular insufficiency.脑干血管疾病中的脑电图;关于脑电图结果与梗死和血管供血不足各种组合关系的一些观察
Electroencephalogr Clin Neurophysiol. 1958 Aug;10(3):405-16. doi: 10.1016/0013-4694(58)90002-6.
10
[EEG aspects of arousal from a coma; cortico-cardio-respiratory correlations].[昏迷觉醒的脑电图特征;皮质-心脏-呼吸相关性]
Presse Med (1893). 1955 Sep 21;63(61):1231-3.