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对一名因中脑和脑桥上部梗死导致昏迷的患者进行丘脑非特异性激活系统的慢性电刺激。

Chronic electrical stimulation of the thalamic unspecific activating system in a patient with coma due to midbrain and upper brain stem infarction.

作者信息

Sturm V, Kühner A, Schmitt H P, Assmus H, Stock G

出版信息

Acta Neurochir (Wien). 1979;47(3-4):235-44. doi: 10.1007/BF01406406.

DOI:10.1007/BF01406406
PMID:314229
Abstract

Chronic intermittent bipolar electrical stimulation of the left nucleus reticulatus polaris thalami was performed in a patient in a state of subcoma due to ischaemic infarction of wide medial parts of the midbrain, mainly the tegmentum, and the right-sided mediobasal parts of the forebrain. Stimulation immediately resulted in autonomic reactions and behavioural arousal reactions during the periods of stimulation. Longterm effect consisted of a rise in the level of clinical responsiveness for a period of seven weeks. A preexistent severe pneumonia disappeared completely after one week of stimulation and returned after seven weeks. The results are discussed on the basis of the pathoanatomical findings and of the physiological functions of the damaged as well as of the stimulated areas.

摘要

对一名因中脑广泛内侧部分(主要是被盖)和前脑右侧中基底部分缺血性梗死而处于昏迷状态的患者,进行了左侧丘脑极网状核的慢性间歇性双相电刺激。刺激期间立即引发了自主反应和行为唤醒反应。长期效果是临床反应水平在七周内有所提高。刺激一周后,先前存在的严重肺炎完全消失,七周后又复发。根据病理解剖学发现以及受损区域和受刺激区域的生理功能对结果进行了讨论。

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