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肠炎沙门氏菌的分子流行病学

Molecular epidemiology of Salmonella enteritidis.

作者信息

Gruner E, Martinetti Lucchini G, Hoop R K, Altwegg M

机构信息

Institute of Medical Microbiology, University of Zurich, Switzerland.

出版信息

Eur J Epidemiol. 1994 Feb;10(1):85-9. doi: 10.1007/BF01717458.

Abstract

Sixteen strains of Salmonella enteritidis isolated in 1991 from 13 unrelated poultry-associated sources, 7 strains from 2 community outbreaks, and 18 human sporadic isolates were investigated by phage typing, analysis of rRNA gene restriction patterns (ribotyping) and plasmid profiles. Four different phage types and 10 SphI patterns were found, whereas plasmids were identical in all but 4 isolates. Only one ribotype (RT A) occurred among both human and avian strains. This particular ribotype was also responsible for the two outbreaks investigated, suggesting that such strains may be of special significance for the increase of S. enteritidis infections.

摘要

1991年从13个无关联的家禽相关来源分离出16株肠炎沙门氏菌,从2起社区疫情中分离出7株,以及18株人类散发病例分离株,通过噬菌体分型、rRNA基因限制性图谱分析(核糖分型)和质粒图谱进行了研究。发现了4种不同的噬菌体类型和10种SphI图谱,而除4株分离株外,所有菌株的质粒均相同。在人类和禽类菌株中仅出现一种核糖型(RT A)。这种特定的核糖型也与所调查的两起疫情有关,表明此类菌株可能对肠炎沙门氏菌感染的增加具有特殊意义。

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