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嗜铬粒蛋白B、分泌粒蛋白II、降钙素基因相关肽和P物质在发育中和成年神经肌肉突触处的免疫定位。

Immunolocalisation of chromogranin B, secretogranin II, calcitonin gene-related peptide and substance P at developing and adult neuromuscular synapses.

作者信息

Andreose J S, Sala C, Fumagalli G

机构信息

C.N.R. Center of Cytopharmacology, Department of Medical Pharmacology, University of Milano, Italy.

出版信息

Neurosci Lett. 1994 Jun 20;174(2):177-80. doi: 10.1016/0304-3940(94)90015-9.

Abstract

The localisation of chromogranin B, secretogranin II, calcitonin gene-related peptide and substance P was characterised by the use of indirect immunofluorescence techniques at neuromuscular junctions in frog, mouse and rat muscles. We found that chromogranin B, secretogranin II and calcitonin gene-related peptide are co-expressed in the frog, 1 week old mouse and 1 week old rat endplates. Substance P immunoreactivity could only be detected in frog muscles.

摘要

运用间接免疫荧光技术,对青蛙、小鼠和大鼠肌肉神经肌肉接头处嗜铬粒蛋白B、分泌粒蛋白II、降钙素基因相关肽和P物质的定位进行了表征。我们发现,嗜铬粒蛋白B、分泌粒蛋白II和降钙素基因相关肽在青蛙、1周龄小鼠和1周龄大鼠的终板中共表达。P物质免疫反应性仅在青蛙肌肉中检测到。

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