妥卡尼的氨基甲酸酯类似物。
Carbamate analogues of tocainide.
作者信息
Cernusková L, Benes L, Csöllei J, Tumová I, Svec P
机构信息
Department of Medicinal Chemistry, Faculty of Pharmacy, Comenius University, Bratislava, Slovak Republic.
出版信息
Pharmazie. 1994 Sep;49(9):646-9.
PMID:7526407
Abstract
A series of the new aminoalkyl esters of chlor-, methyl- and alkoxy carbanilates was synthesized. All the compounds prepared were found to exhibit antiarrhythmic activities comparable with those of mexiletine.
摘要
合成了一系列氯代、甲基和烷氧基氨基甲酸酯的新型氨基烷基酯。发现所有制备的化合物均表现出与美西律相当的抗心律失常活性。
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